Thursday, 7 April 2016

What are the challenges of conducting pragmatic trials (PCTs)?

Iris Goetz
Global Health Outcomes
Eli Lilly, UK

Get REAL PRoject 
IMI Work Package WP3 

Focus on randomisation
RCT in real world !

consequences of design
consequences of design choice

key activities
ensure feasibility while keeping validity
literature review
practical solutions
stakeholders interviews

Definition of pragmatic trials -various- 
mainly  trials comparing different health interventions -effectiveness

Comparing RCT (randomised clinical trials) with PCT (pragmatic clinical trials)

Which design criteria important in designing a PCT?

Comparison of Treatments Arms -questions to be answered
Baseline-do we need wash-out period?
link hospital data with the GP data

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